He was first to do a major surgical operation with ether anesthesia, pp. 226-251. The operation was an amputation of the thigh. It was performed by Hayward the day after Warren's initial spectacular demonstration. At this second operation Morton was again the anaesthetist. The book is replete with important surgical monographs. There are chapters on diseases of the knee joint, statistics on amputations, and division of tendons. Most of the clinical observations were made at the Massachusetts General Hospital and some of the statistical data are for the period from the opening of the Hospital, 1822 to 1840. The book is very scarce. -- H.W. Orr.

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