Eight months have passed since vampires released the Revenant Virus on mankind, nearly wiping out both species. For Mike Robson, the situation could be far worse. He has joined up with a small band of humans and the last coven of vampires who are riding out the zombie apocalypse in an old fort along the coast of southern Maine. The uneasy alliance between humans and vampires is strained with the arrival of the creator of the Revenant Virus. Compton claims to have a vaccine that will make humans immune to the virus and allow mankind to take civilization back from the living dead. However, the vaccine is located in a secure underground facility five hundred miles away. To retrieve the vaccine, Robson leads a raiding party of humans and vampires down the East Coast, which has been devastated by the outbreak and overrun by zombies and gangs. None of the horrors he deals with on the road can prepare him for what his team will find in Pennsylvania. Once inside the underground facility, Robson encounters the greatest threat his group has faced to date, not only from zombies but from betrayal within their own ranks.