Now, with the move towards more patient focused health care and at the same time increased emphasis on health economics, evidence-based practice is a more important force in health care delivery than ever. This new third edition, written by the world's leading cardiologists, provides graded evidence-based reviews of the major trials together with recommendations for optimum management, and now includes new grading and recommendation methodology. This is a unique book in the field of cardiology, and the largest evidence based clinical cardiology text.