Contains extensive revisions to reflect the most recent advances, and a new case study companion text offering real life applications of the basic science in a clinical setting. All review questions and additional problems and quizzes have been updated in the dedicated website, which now offers animations as well. As with the previous editions, the strength of the text is in complete coverage of all key topics in modern immunology without overburdening the reader with excessive data or theoretical discussions. Each chapter is divided into short, self-contained units that address key topics illustrated by uniformly drawn, full color illustrations. Includes an all new chapter on immuno-based therapies as well as completely rewritten coverage of complements.