The Second Edition of this comprehensive reference combines a strong scientific base with a clinical focus to address the principal disorders of bone and mineral metabolism, including osteoporosis, kidney stone formation, abnormal serum mineral levels, Paget's disease, and other conditions. The contributors examine normal bone structure and mineral metabolism throughout the life cycle, explain the mechanisms underlying each disorder, and provide succinct guidance on evaluation and management. This edition describes recently introduced drugs, thoroughly reviews powerful new treatments for osteoporosis and nephrolithiasis and also features completely rewritten chapters on stone formation. Over than 500 illustrations complement the text plus over 150 tables help readers find needed information at a glance.