The book investigates different pre-Columbian and more recent geohistorical processes, from archaeological traces located in the region that goes from the western limit of the province of Darién, in Panama, to the southern limit of the department of Chocó, in Colombia. Attention is drawn to the emptiness of archaeological studies about this area, whose place in the settlement of South America, by the west towards the Andes, has not been fully dimensioned and tested, like other geohistorical processes of the region on which it has been investigated a little groping, based on scarce material evidence. The book investigates different pre-Columbian and more recent geohistorical processes, from archaeological traces located in the region that goes from the western limit of the province of Darién, in Panama, to the southern limit of the department of Chocó, in Colombia. Attention is drawn to the emptiness of archaeological studies about this area, whose place in the settlement of South America, by the west towards the Andes, has not been fully dimensioned and tested, like other geohistorical processes of the region on which it has been investigated a little groping, based on scarce material evidence.