Karima "C.R.E.A.M." Thomas, who has been held as an accomplice in the murders of two drug dealers, is acquitted based on the deathbed confession of her lover, Duane Faison. But triumph soon turns to tragedy when Karima's mother is found dead of an apparent suicide. Karima refuses to believe that things are as they seem. She suspects that her mother was murdered, and when the police won't listen, she takes matters into her own hands.