This report highlights key issues to facilitate understanding of how a systemic approach to technology-based school innovations can contribute to quality education for all while promoting a more equal and effective education system. It focuses on the novel concept of systemic innovation, as well as presenting the emerging opportunities to generate innovations that stem from Web 2.0 and the important investments and efforts that have gone into the development and promotion of digital resources. It also shows alternative ways to monitor, assess and scale up technology-based innovations. Some country cases, as well as fresh and alternative research frameworks, are presented. Today, sufficient return on public investments in education and the ability to innovate are more important than ever. This was the conclusion of the international conference on "The School of Tomorrow, Today" organised by the OECD Centre for Educational Research and Innovation with the support of the Secretariat of Education of the State Santa Catarina (Brazil), in November 2009. The conference and this resulting report share the overall goal of addressing the issue of how education systems achieve technology-based innovations.