While few would still hold forensic DNA analysis for the cure-all for unsolved crimes that many once believed it to be, DNA evidence now clearly ranks as one of the most powerful types of forensic evidence available. In addition to its unrivalled potential to eliminate the innocent and include the potentially guilty, it has proved its capacity to produce a decisive breakthrough in hitherto unsolved crimes. Furthermore, it has been instrumental in resolving miscarriages of justice, thereby revealing the limitations of many traditional types of evidence, including (eye)witness evidence. 00Little is known about the actual effectiveness of the transnational DNA profile exchange in bringing cases to court. Here, the follow-up of a match is the key issue. No follow-up means no added value for the resolution of crimes. Therefore, a true measure of the effectiveness of the exchange process is not obtained by just counting the number of detected matches but by examining how many matches eventually play a role in criminal investigations.00This book reports on just such a study. It looks at the effectiveness of the exchange and comparison of DNA profiles between various European countries, more specifically between the Netherlands and Austria, Bulgaria, Finland, France, Germany, Luxembourg, Slovakia, Slovenia and Spain. The study follows the route of transnational DNA matches detected in 2010 through the Dutch legal system. It appears that some 6% of these matches make it to court. One of the more striking findings of the study is the difference observed between follow-up figures for border as opposed to non-border regions. 0 0The study was undertaken as part of the larger PIES project (Prüm Implementation, Evaluation and Strengthening of forensic DNA data exchange) carried out on behalf of the European Commission, Directorate General Home Affairs.