When Tilly receives an invitation to help drive eight elders on their ultimate bucket-list road trip, she impulsively says yes. Before she knows it, Tilly has said good-bye to her family and is on an adventure that will transform her in ways she could not predict, just as it will for the elders who soon dub themselves the "Crazy Eights". They each choose a stop, somewhere or something they've always wanted to experience, on the way to their ultimate goal, the Gathering of Nations Pow Wow in Albuquerque. Their plan is to travel to Las Vegas, Sedona, and the Redwood Forests, with each destination the inspiration for secrets and stories to be revealed. The trip proves to be powerful medicine as they laugh, heal, argue, and dream along the way. By the time their bus rolls to a stop in New Mexico, Tilly and the Crazy Eights, with friendships forged and hearts mended, feel ready for anything. But are they?