Chapters 5 and 6 deal with relations belonging to the family of simple dependence, among others (i) generic dependence, (ii) various forms of temporal dependence, and (iii) supervenience, a complex dependence relation largely invoked in current debates on the philosophy of mind. It is shown that foundationalist accounts of these notions - i.e. accounts framed in terms of grounding - are superior to other existing accounts. These chapters also contain some applications of the foundational conception of dependence, in particular a characterization of substances and a formulation of the distinction between two well known conceptions of universals, the Aristotelian and the Platonician conception. The last part of the work is a technical appendix where one can find, among other things, a system for the logic of essence, which is proved to be sound and complete with respect to a possible world semantics.