Two dozen papers present theories on the molecular and genetic mechanisms responsible for the development of glucose intolerance in non-insulin-dependent diabetes mellitus. They cover the regulation of insulin secretion; insulin, insulin receptors, and glucose transporters; insulin action; gluconeogenesis; obesity, lipoproteins, and atherogenesis; and how new concepts for delivering care to diabetic populations may impact non-insulin- dependent diabetes mellitus. Reproduced from typescripts, some double spaced.