The goal of The Science of Prevention: Methodological Advances From Alcohol and Substance Abuse Research is to promote critical thinking among new and established investigators about how to design research and analyze research findings. Although the substantive focus of many chapters is on applications to the prevention of alcohol and substance abuse, nearly all of the methodological principles and statistical models are general and have potential application to the full range of areas in which prevention research takes place. The contributors to this book share their knowledge from an informed, applied perspective. Most are active researchers in the field of substance abuse prevention who are also methodological experts. They have a firsthand knowledge not only of the methodological, statistical, and measurement issues but also of the substantive issues of their field.