This book is a compendium of original contributions that focus on new developments and applications for the Minnesota Multiphasic Personality Inventory (MMPI-2), the most widely researched and broadly used personality assessment instrument. This handbook, which is specifically geared for clinicians and graduate students, addresses both research and clinical applications of the MMPI-2. The contributors to this volume are a distinguished team of psychologists with established expertise in both assessment research and practical contributions to test interpretation. The chapters cover theoretical issues that affect the interpretation of the MMPI-2 in a wide range of circumstances, such as the presence of neurological injury, PTSD, or substance abuse, as well as in particular settings and with diverse populations. An overview of current relevant research underlying each specific application is provided along with established guidelines for administration and interpretation of the MMPI-2 in the test application.