Over the last 20 years, fundamental design concepts and advanced computer modeling have revolutionized process design for chemical engineering. Team work and creative problem solving are still the building blocks of successful design, but new design concepts and novel mathematical programming models based on computer-based tools have taken out much of the guess-work. This book presents the new revolutionary knowledge, taking a systematic approach to design at all levels. Systematic Methods of Chemical Process Design is a textbook for undergraduate and graduate design courses. The book presents a step-by-step approach for learning the techniques for synthesizing and analyzing process flowsheets. The major items involved in the design process are mirrored in the book's main sections: strategies for preliminary process analysis and evaluation, advanced analysis using rigorous models, basic concepts in process synthesis, optimization models for process synthesis and design, and appendices for reference and review. Developed and refined in several courses at Carnegie Mellon, preliminary versions of the book have also been tested in Argentina, Brazil, England, Korea, Norway, and Slovenia. Exercises at the end of each chapter make it suitable for teaching both undergraduate and graduate courses, or for the working professional who wants to keep up with current methods.