This new text delivers a foundation for understanding the role of genomics in human health and in advances that promise to help improve the quality of human life. Unlike other works that focus mainly on toxico-genomic techniques, Genomics presents a overview of the field in three major sections: 1) fundamentals of genes and genome structure, function, expression, variations, and genomic technology platforms; 2) applications of genomics in drug discovery and drug development, safety evaluation, genomic database maintenance, mining, and analysis, food safety monitoring, and translational toxicogenomics; and 3) how regulatory agencies such as the FDA and EPA use genomic data in their safety evaluation.