Covers disorders capable of directly or indirectly causing death of the patient. The book is organized around four sections dealing with dermatologic diseases involving serious cutaneous malignancies including melanoma; life-threatening and/or emerging infectious pathogens including anthrax and smallpox; endocrinologic disorders such as myxedema or calciphylaxis; autoimmune disorders and inborn errors of metabolism such as scleroderma and hemochromatosis. The sections are organized alphabetically and color-coded for easy reference. Approximately 40 disease states are discussed with accompanying full-color clinical and microscopic photography. Each entity contains a single clinical photograph accompanied by three photomicrographs detailing the diagnostic features of each case. Subsections detailing the demographic attributes, etiology, pathogenesis, clinical presentation, pathologic features, diagnostic adjuncts, treatment, and prognosis with a current bibliography of each dis.