This work takes us into the Darwin family's private world to tell the story of Charles and Emma Darwin's and their first daughter Annie, who died at the age of ten. When Annie was a baby, Darwin doted on her, but also watched her with his researches in mind, and thought about man's animal origins. As Annie grew into a lively child, Darwin worked secretly on his theory of evolution, but his ideas were just one part of the family's life amid the wealth and poverty of Victorian England. Randal Keynes, Darwin's great-great-grandson and the current guardian of Annie's box, conjures up a world in which great thinkers - including Carlyle, Babbage and George Eliot - were struggling with ideas that were to shake mankind to its core.