Newly appointed principal research investigators have to recruit, motivate, and lead a research team, manage personnel and institutional responsibilities, and compete for funding while maintaining the outstanding scientific record that got them their position in the first place. In this book, the author provides a guide for newly appointed leaders of research teams, and those who aspire to that role. With extensive use of interviews and a text enlivened with quotes and real-life examples, it discusses a wide range of management challenges and the skills that promote success.