This book provides a comprehensive review of the related literature, while providing insights into the obstacles of improved survival and discuss methods to advance the field of Bladder Cancer care. The work aims to spur innovative thoughts and approaches to common problems in the management of early stage and advanced disease. The book discusses at length the state of bladder cancer staging and the optimal treatment for localized disease. Additional sections review the applications of existing systemic therapies and look at the infrastructure needed to support translational research efforts.