Dan and Carmen are hip, healthy and wealthy. They have their own companies, plenty of money and friends and are the proud parents of one year-old Luna. They live the cool life in Amsterdam, until beautiful and optimistic Carmen is diagnosed with breast cancer. With that their world transforms into a roller-coaster ride of doctors and hospitals. As his way of coping, the hedonistic Dan faithfully accompanies Carmen to her chemo and radiotherapy treatments, but spends his nocturnal hours crazily immersed in the nightlife and women of Amsterdam and Miami.