This volume is the first full-length biography of Sydney Brenner,the Nobel-Prize-winning scientist whose brilliant career has encompassed fundamental insights into the functions of RNA, the genetic code, and the principles of animal development, as well as leadership of research institutions in the USA, Singapore, and Japan. Known for his creativity, acerbic wit, and generosity to colleagues, and indefatigable even in his eighties, Brenner is one of the most influential scientists of our time.