"In this book, international experts review the contribution of trypanosome research to our understanding of eukaryote biology: Chapters are written from a molecular and genomic perspective and contain speculative models upon which to base future research efforts. Topics include the genome of T. brucei; reverse and forward genetics; genetic exchange between trypanosomes; chromosome structure and dynamics; DNA replication, recombination, and repair; transcription; post-transcriptional control of gene expression; cell structure, cell division, and cell cycle; intracellular transport systems; cell surface architecture; antigenic variation; and comparative genomics of metabolism. This book provides a resource summarizing our current knowledge of trypanosome molecular and cellular biology."--Jacket.