This report discusses the technical details associated with nuclear disarmament. From the text: "Measured steps are essential to progress towards the eventual elimination of nuclear arsenals. Science and technology (S&T) will play a critical role in balancing deterrence with nuclear arsenal downsizing and in achieving nuclear nonproliferation objectives. In particular, S&T can help manage three key goals associated with this vision: 1) verifying the process of downsizing and dismantling of stockpiles, 2) sustaining nuclear weapons capability and expertise for as long as is necessary, and 3) removing the capabilities for reversals through various confidence-building measures, in particular by ensuring the peaceful use of fissile materials."