Intense research into the eukaryotic cell cycle has resulted in major advances in this field. The use of recombinant DNA and related technologies has revealed the extraordinary degree to which cell-cycle control mechanisms have been conserved through eukaryotic evolution. Furthermore, these and other techniques are now allowing the mechanisms of cell-cycle regulation to be understood in fine detail. This book brings together for the first time all the main biochemical, genetic, and cellular manipulations required for cell-cycle investigations in the most popular experimental systems: yeasts and fungi, amphibian and marine invertebrate eggs, insects, and vertebrate cells. The Cell Cycle: A Practical Approach is a timely bench manual which gives clear and detailed practical guidance for all those interested in studies of the eukaryotic cell cycle, whether they are molecular biologists, geneticists, biochemists, or cell biologists.