Dora and her old enemy Lucy are paired up on the children's ward for the final three months of their training. The two nurses couldn't be more different, but they have more in common than they think, as they each hide a secret heartache. And the new trainee nurse Effie can't wait to escape her small Irish village, and make her way as a nurse in London. But Effie's sister Katie soon begins to worry that Effie's behaviour is out of control. And Jess the feisty eldest daughter of a notorious East End family is determined to prove herself as a maid.