This biography focuses on Clark's tenure as Indian agent, territorial governor, and Superintendent of Indian Affairs at St. Louis. Responsible for one-tenth of all Indian treaties ratified by the U.S. Senate, Clark was ultimately responsible for dispossessing more Indians than perhaps any other American, even if he sympathized with the Indians' fate and felt compassion for Native peoples. This books show the immense influence that Clark had on Indian-White relations in the trans-Mississippi region and on federal Indian policy in general.