This book overviews our current understanding of the biology of liver metastases, and reviews current methods of detection and diagnosis. Thereafter, the chapters offer objective and systematic reviews of each of the current major treatment modalities: surgical resection; destructive therapies; chemotherapy (systemic and regional); whether there is a role for radiotherapy; biological therapies (including hormone treatment antibodies and gene therapy); and lastly the decision making strategies that must be employed for successful multidisciplinary management. The book concludes with an overview of the health economics issues that must be addressed by all who practice in the field of treatment of liver metastases. The book will be invaluable for surgeons in general surgery, hepatobiliary surgery, upper GI surgery, colorectal surgery, medical and clinical oncologists with an interest in liver tumours, and radiologists with an interest in liver disease.