This book relies on multiple short chapters that have been designed to make the information accessible and comprehensive to the expert in nephrology and hypertension and the general internist, fellow, or student. Clinical features, pathology, pathophysiology, and diagnosis are discussed only briefly to launch a detailed discussion of therapy. With regard to hypertension, the sections on the management of essential and secondary hypertension have been expanded significantly, reflecting the impressive volume of new clinical trial activity in these areas. This book assists the reader with the management of their patients and with the design of new therapeutic strategies and regimens that will advance the treatment of renal disease and hypertension going forward.