The author raises the hypothesis, verified by the rigor of the corresponding research and analysis, that there was in Egypt and Mesoamerica an identical design system based on astronomical numerology, which allowed the sizing of architecture and art. It is shown in the studied works that both peoples followed precise astronomical and mathematical charges in search of the representation and correspondence of their works with astronomical and/or calendarical cycles. In these pages the reader will find mathematical calculations of the surfaces and volumes of monuments and important objects typical of those cultures that indicate cosmogonies and similar cultures that coincide in the explanation of their world despite the geographical and temporal distance that separates them. It is shown that no work of Art or Egyptian or Mesoamerican architecture was performed at random or left to improvisation, but following strict purposes of astronomical communication, mathematics, numerological and sacred, which could be summed up in the obsessive intention of both peoples to achieve life after death.